Journal of Research in Medical Sciences

SHORT COMMUNICATION
Year
: 2022  |  Volume : 27  |  Issue : 1  |  Page : 47-

Quantity of the antigens of Streptococcus mutans serotype e and Candida albicans and its correlation with the salivary flow rate in early childhood caries


Endang Winiati Bachtiar1, Vanya A Kusuma1, Ferry P Gultom1, Retno D Soejoedono2 
1 Department of Oral Biology, Oral Science Research Center, Faculty of Dentistry, Universitas Indonesia, Jakarta, Indonesia
2 Department of Immunology, Faculty of Veterinary, IPB University, Dramaga Campus, Bogor, Indonesia

Correspondence Address:
Prof. Endang Winiati Bachtiar
Department of Oral Biology, Oral Science Research Center, Faculty of Dentistry, Universitas Indonesia, Jalan Salemba No. 4, Jakarta 10430
Indonesia

Background: Streptococcus mutans involved in caries pathogenesis is classified into four serotypes, namely serotypes c, e, f, and k. Candida albicans can be found in the plaque of children with early childhood caries (ECC). Aims: The aim of this study was to analyze the quantity of the antigens of S. mutans serotype e and C. albicans and its correlation with the salivary flow rate in ECC. Materials and Methods: The antigen quantities of caries plaque samples and caries-free were determined using an enzyme-linked immunoassay with 450-nm optical density. Results: There was a significant difference between the quantity of S. mutans serotype e and C. albicans antigens in each salivary flow rate category (P < 0.05). The relationship between the antigen quantity of S. mutans serotype e and C. albicans was r = 0.624 (P > 0.05) for caries plaque samples and r = 0.628 (P > 0.05) for caries-free samples. Conclusion: the antigen quantities of S. mutans serotype e and C. albicans and the salivary flow rate might correlate to the pathogenesis of ECC.


How to cite this article:
Bachtiar EW, Kusuma VA, Gultom FP, Soejoedono RD. Quantity of the antigens of Streptococcus mutans serotype e and Candida albicans and its correlation with the salivary flow rate in early childhood caries.J Res Med Sci 2022;27:47-47


How to cite this URL:
Bachtiar EW, Kusuma VA, Gultom FP, Soejoedono RD. Quantity of the antigens of Streptococcus mutans serotype e and Candida albicans and its correlation with the salivary flow rate in early childhood caries. J Res Med Sci [serial online] 2022 [cited 2023 Jan 30 ];27:47-47
Available from: https://www.jmsjournal.net/article.asp?issn=1735-1995;year=2022;volume=27;issue=1;spage=47;epage=47;aulast=Bachtiar;type=0