Journal of Research in Medical Sciences

ORIGINAL ARTICLE
Year
: 2021  |  Volume : 26  |  Issue : 1  |  Page : 106-

Comparison of hemodynamic changes and serum potassium levels in the use of succinylcholine and cisatracurium in electroconvulsive therapy


Behzad Nazemroaya1, Atefeh Ghosouri2, Azim Honarmand2, Seyed Taghi Hashemi2 
1 Anaesthesiology and Critical Care Research Centre, Isfahan University of Medical Sciences, Isfahan, Iran
2 Department of Anaesthesiology and Critical Care, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Correspondence Address:
Behzad Nazemroaya
Department of Anaesthesiology and Critical Care, Anaesthesiology and Critical Care Research Centre, School of Medicine, Isfahan University of Medical Sciences, Isfahan
Iran

Background: Electroconvulsive therapy (ECT) is nowadays used commonly as one the most effective treatment methods in psychiatric disorders. In patients undergoing ECT, succinylcholine is usually used. In addition, cisatracurium is occasionally used on a case report basis globally. In this study, we compared the hemodynamic changes and serum potassium levels in the use of succinylcholine and cisatracurium in ECT. Materials and Methods: The current crossover clinical trial was performed on 45 patients who were candidates for ECT between 2017 and 2018. The patients were given succinylcholine or cisatracurium randomly on two separate occasions of ECT. The independent t-test and Chi square Test were used to compare the data. Results: Comparison of mean systolic blood pressure (P = 0.14), diastolic blood pressure (P = 0.33), and mean arterial pressure (P = 0.23) did not show any significant difference between the two groups. The induced seizure duration (P = 0.002), return of spontaneous respiratory from seizure ending (P = 0.001), and apnea duration (P = 0.01) were significantly higher in the cisatracurium group compared to the succinylcholine group. However, the frequency of tachycardia in cisatracurium group was lower than the succinylcholine group (P < 0.001). In addition, the serum potassium level had a significant difference (P < 0.001) between the two groups. Conclusion: Using cisatracurium can be an alternative to succinylcholine during ECT since it causes less elevation in serum potassium and creates a longer duration of induced seizure, more rapid re emergence of spontaneous breathing at the end of seizure (P = 0.001), and a lower prevalence of tachycardia compared to succinylcholine (P < 0.001).


How to cite this article:
Nazemroaya B, Ghosouri A, Honarmand A, Hashemi ST. Comparison of hemodynamic changes and serum potassium levels in the use of succinylcholine and cisatracurium in electroconvulsive therapy.J Res Med Sci 2021;26:106-106


How to cite this URL:
Nazemroaya B, Ghosouri A, Honarmand A, Hashemi ST. Comparison of hemodynamic changes and serum potassium levels in the use of succinylcholine and cisatracurium in electroconvulsive therapy. J Res Med Sci [serial online] 2021 [cited 2022 Dec 2 ];26:106-106
Available from: https://www.jmsjournal.net/article.asp?issn=1735-1995;year=2021;volume=26;issue=1;spage=106;epage=106;aulast=Nazemroaya;type=0