| 1 |
Rotenone-Induced Model of Parkinson’s Disease: Beyond Mitochondrial Complex I Inhibition |
|
|
| María Teresa Ibarra-Gutiérrez, Norma Serrano-García, Marisol Orozco-Ibarra |
|
| Molecular Neurobiology. 2023; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 2 |
Polymorphic Alpha-Synuclein Oligomers: Characterization and Differential Detection with Novel Corresponding Antibodies |
|
|
| Kenya Moore, Urmi Sengupta, Nicha Puangmalai, Nemil Bhatt, Rakez Kayed |
|
| Molecular Neurobiology. 2023; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 3 |
Hybrids of polyphenolic/quinone acids, the potential preventive and therapeutic drugs for PD: Disaggregate a-Syn fibrils, inhibit inclusions, and repair damaged neurons in mice |
|
|
| Ming-Huan Lü, Zhen-Ping Wang, Li-Zi Xing, Wei Zhang, Feng Han, Guo-Long Huang, Wei Liu, Yun-Xiao Zhang, Ji Xu, Jinquan Cui |
|
| European Journal of Medicinal Chemistry. 2023; 249: 115122 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 4 |
Curcumin Modulates p62–Keap1–Nrf2-Mediated Autophagy in Rotenone-Induced Parkinson’s Disease Mouse Models |
|
|
| Aaina Singh Rathore, Saumitra Sen Singh, Hareram Birla, Walia Zahra, Priyanka Kumari Keshri, Hagera Dilnashin, Richa Singh, Shekhar Singh, Surya Pratap Singh |
|
| ACS Chemical Neuroscience. 2023; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 5 |
Mitochondrial Complex I as a Pathologic and Therapeutic Target for Parkinson’s Disease |
|
|
| Kamatham Pushpa Tryphena, Uppala Sai Nikhil, Poojitha Pinjala, Saurabh Srivastava, Shashi Bala Singh, Dharmendra Kumar Khatri |
|
| ACS Chemical Neuroscience. 2023; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 6 |
Metabolism and memory: a-synuclein level in children with obesity and children with type 1 diabetes; relation to glucotoxicity, lipotoxicity and executive functions |
|
|
| Nouran Yousef Salah, Sara Ibrahim Taha, Safeya Hassan, Mai Seif ElDin Abdeen, Mostafa Ahmad Hashim, Rana Mahmoud |
|
| International Journal of Obesity. 2022; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 7 |
Mechanisms of NLRP3 activation and pathology during neurodegeneration |
|
|
| Sara Jose, Natalie J Groves, Kathrein E. Roper, Richard Gordon |
|
| The International Journal of Biochemistry & Cell Biology. 2022; : 106273 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 8 |
Liquid-liquid Phase Separation of a-Synuclein: A New Mechanistic Insight for a-Synuclein Aggregation Associated with Parkinson's Disease Pathogenesis |
|
|
| Semanti Mukherjee, Arunima Sakunthala, Laxmikant Gadhe, Manisha Poudyal, Ajay Singh Sawner, Pradeep Kadu, Samir K. Maji |
|
| Journal of Molecular Biology. 2022; : 167713 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 9 |
Effects of Mutations and Post-Translational Modifications on a-Synuclein In Vitro Aggregation |
|
|
| Samantha X. Pancoe, Yanxin J. Wang, Marie Shimogawa, Ryann M. Perez, Sam Giannakoulias, E. James Petersson |
|
| Journal of Molecular Biology. 2022; : 167859 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 10 |
Detection and assessment of alpha-synuclein in Parkinson disease |
|
|
| Hsien-Hao Tsao, Chung-Guei Huang, Yih-Ru Wu |
|
| Neurochemistry International. 2022; : 105358 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 11 |
Structural and mechanistic insights into modulation of a-Synuclein fibril formation by aloin and emodin |
|
|
| Vinod Kumar Meena, Vijay Kumar, Shivani Karalia, Rohit Sing Dangi, Monica Sundd |
|
| Biochimica et Biophysica Acta (BBA) - General Subjects. 2022; : 130151 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 12 |
a-Synuclein interacts differently with membranes mimicking the inner and outer leaflets of neuronal membranes |
|
|
| Samira Jadavi, Ester Canepa, Alberto Diaspro, Claudio Canale, Annalisa Relini, Silvia Dante |
|
| Biochimica et Biophysica Acta (BBA) - Biomembranes. 2022; 1864(1): 183814 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 13 |
Inhibition of Amyloid Protein Aggregation Using Selected Peptidomimetics |
|
|
| Debabrata Maity |
|
| ChemMedChem. 2022; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 14 |
Glycation of a-synuclein hampers its binding to synaptic-like vesicles and its driving effect on their fusion |
|
|
| Ana Belén Uceda, Juan Frau, Bartolomé Vilanova, Miquel Adrover |
|
| Cellular and Molecular Life Sciences. 2022; 79(6) |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 15 |
Molecular Insights into the Misfolding and Dimerization Dynamics of the Full-Length a-Synuclein from Atomistic Discrete Molecular Dynamics Simulations |
|
|
| Yu Zhang, Ying Wang, Yuying Liu, Guanghong Wei, Feng Ding, Yunxiang Sun |
|
| ACS Chemical Neuroscience. 2022; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 16 |
Associations between cerebrospinal fluid markers and cognition in ageing and dementia: A systematic review |
|
|
| Tyler S. Saunders, Danni A. Gadd, Tara L. Spires-Jones, Declan King, Craig Ritchie, Graciela Muniz-Terrera |
|
| European Journal of Neuroscience. 2022; 56(9): 5650 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 17 |
Potential biomarkers of addiction identified by real-time PCR in human peripheral blood lymphocytes: a narrative review |
|
|
| Shahrzad Nazari, Seyed Mahmoud Pourmand, Seyed Mohammad Makki, Serge Brand, Nasim Vousooghi |
|
| Biomarkers in Medicine. 2022; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 18 |
DNA methylation as a mediator of genetic and environmental influences on Parkinson’s disease susceptibility: Impacts of alpha-Synuclein, physical activity, and pesticide exposure on the epigenome |
|
|
| Samantha L. Schaffner, Michael S. Kobor |
|
| Frontiers in Genetics. 2022; 13 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 19 |
Proteomics Challenges for the Assessment of Synuclein Proteoforms as Clinical Biomarkers in Parkinson’s Disease |
|
|
| Marie-Laure Pons, Neil Loftus, Jerome Vialaret, Stephane Moreau, Sylvain Lehmann, Christophe Hirtz |
|
| Frontiers in Aging Neuroscience. 2022; 14 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 20 |
Protective Effects of Polysaccharides in Neurodegenerative Diseases |
|
|
| Yinying Wang, Rongsha Chen, Zhongshan Yang, Qian Wen, Xia Cao, Ninghui Zhao, Jinyuan Yan |
|
| Frontiers in Aging Neuroscience. 2022; 14 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 21 |
The relationship of alpha-synuclein to mitochondrial dynamics and quality control |
|
|
| Naomi J. Thorne, David A. Tumbarello |
|
| Frontiers in Molecular Neuroscience. 2022; 15 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 22 |
Lysophospholipids: A Potential Drug Candidates for Neurodegenerative Disorders |
|
|
| Tatsuya Karaki, Hisao Haniu, Yoshikazu Matsuda, Tamotsu Tsukahara |
|
| Biomedicines. 2022; 10(12): 3126 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 23 |
Influence of Urea and Dimethyl Sulfoxide on K-Peptide Fibrillation |
|
|
| Jaroslaw Wawer, Jakub Karczewski, Robert Aranowski, Rafal Piatek, Danuta Augustin-Nowacka, Piotr Bruzdziak |
|
| International Journal of Molecular Sciences. 2022; 23(6): 3027 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 24 |
A Microplate-Based Approach to Map Interactions between TDP-43 and a-Synuclein |
|
|
| Angelo M. Jamerlan, Seong Soo A. An |
|
| Journal of Clinical Medicine. 2022; 11(3): 573 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 25 |
Role of post-translational modifications on the alpha-synuclein aggregation-related pathogenesis of Parkinson’s disease |
|
|
| Hajung Yoo, Jeongmin Lee, Bokwang Kim, Heechang Moon, Huisu Jeong, Kyungmi Lee, Woo Jeung Song, Junho K. Hur, Yohan Oh |
|
| BMB Reports. 2022; 55(7): 323 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 26 |
Biomarkers of Major Depressive Disorder: Knowing is Half the Battle |
|
|
| Sahil Malik,Ravinder Singh,Govind Arora,Akriti Dangol,Sanjay Goyal |
|
| Clinical Psychopharmacology and Neuroscience. 2021; 19(1): 12 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 27 |
Sgt1 Regulates a-Synuclein Subcellular Localization and Expression of Parkinson’s Disease Related Genes, PINK1 and PARK9 |
|
|
| Anastasiia Bohush, Agnieszka Góral, Malgorzata Sierant, Barbara Nawrot, Wieslawa Lesniak, Anna Filipek |
|
| Biomolecules. 2021; 11(11): 1675 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 28 |
A novel multi-target strategy to attenuate the progression of Parkinsonæs disease by diamine hybrid AGE/ALE inhibitor |
|
|
| N André Sasaki,Pascal Sonnet |
|
| Future Medicinal Chemistry. 2021; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 29 |
Structural and Functional Changes of Reconstituted High-Density Lipoprotein (HDL) by Incorporation of a-synuclein: A Potent Antioxidant and Anti-Glycation Activity of a-synuclein and apoA-I in HDL at High Molar Ratio of a-synuclein |
|
|
| Kyung-Hyun Cho |
|
| Molecules. 2021; 26(24): 7485 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 30 |
Oxidative stress factors in Parkinson’s disease |
|
|
| Jolanta Dorszewska,Marta Kowalska,Michal Prendecki,Thomas Piekut,Joanna Kozlowska,Wojciech Kozubski |
|
| Neural Regeneration Research. 2021; 16(7): 1383 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 31 |
Interaction between Parkin and a-Synuclein in PARK2-Mediated Parkinson’s Disease |
|
|
| Daniel Aghaie Madsen,Sissel Ida Schmidt,Morten Blaabjerg,Morten Meyer |
|
| Cells. 2021; 10(2): 283 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 32 |
MicroRNAs, Parkinson’s Disease, and Diabetes Mellitus |
|
|
| Hsiuying Wang |
|
| International Journal of Molecular Sciences. 2021; 22(6): 2953 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 33 |
Further Characterization of Intrastriatal Lipopolysaccharide Model of Parkinson’s Disease in C57BL/6 Mice |
|
|
| Isaac Deng,Frances Corrigan,Sanjay Garg,Xin-Fu Zhou,Larisa Bobrovskaya |
|
| International Journal of Molecular Sciences. 2021; 22(14): 7380 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 34 |
Mechanistic Insight from Preclinical Models of Parkinson’s Disease Could Help Redirect Clinical Trial Efforts in GDNF Therapy |
|
|
| Karen M. Delgado-Minjares, Daniel Martinez-Fong, Irma A. Martínez-Dávila, Cecilia Bañuelos, M. E. Gutierrez-Castillo, Víctor Manuel Blanco-Alvarez, Maria-del-Carmen Cardenas-Aguayo, José Luna-Muñoz, Mar Pacheco-Herrero, Luis O. Soto-Rojas |
|
| International Journal of Molecular Sciences. 2021; 22(21): 11702 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 35 |
The Neuroprotective Effects of Cannabis-Derived Phytocannabinoids and Resveratrol in Parkinson’s Disease: A Systematic Literature Review of Pre-Clinical Studies |
|
|
| Samay Prakash, Wayne G. Carter |
|
| Brain Sciences. 2021; 11(12): 1573 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 36 |
Beyond Neuronal Microtubule Stabilization: MAP6 and CRMPS, Two Converging Stories |
|
|
| Camille Cuveillier,Benoit Boulan,Charlotte Ravanello,Eric Denarier,Jean-Christophe Deloulme,Sylvie Gory-Fauré,Christian Delphin,Christophe Bosc,Isabelle Arnal,Annie Andrieux |
|
| Frontiers in Molecular Neuroscience. 2021; 14 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 37 |
14-3-3 mitigates alpha-synuclein aggregation and toxicity in the in vivo preformed fibril model |
|
|
| Rachel Underwood,Mary Gannon,Aneesh Pathak,Navya Kapa,Sidhanth Chandra,Alyssa Klop,Talene A. Yacoubian |
|
| Acta Neuropathologica Communications. 2021; 9(1) |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 38 |
Mechanistic roles for altered O-GlcNAcylation in neurodegenerative disorders |
|
|
| Aaron T. Balana,Matthew R. Pratt |
|
| Biochemical Journal. 2021; 478(14): 2733 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 39 |
Molecular insights into
a-synuclein
interaction with individual human core histones, linker histone, and
dsDNA |
|
|
| Sneha Jos,Hemanga Gogoi,Thazhe Kootteri Prasad,Manjunath A. Hurakadli,Neelagandan Kamariah,Balasundaram Padmanabhan,Sivaraman Padavattan |
|
| Protein Science. 2021; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 40 |
Toxic Feedback Loop Involving Iron, Reactive Oxygen Species, a-Synuclein and Neuromelanin in Parkinson’s Disease and Intervention with Turmeric |
|
|
| Zuné Jansen van Rensburg,Shameemah Abrahams,Soraya Bardien,Colin Kenyon |
|
| Molecular Neurobiology. 2021; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 41 |
PARkinsonæs: From cellular mechanisms to potential therapeutics |
|
|
| Zsofia Lengyel-Zhand,Laura N. Puentes,Robert H. Mach |
|
| Pharmacology & Therapeutics. 2021; : 107968 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 42 |
Biosensor approaches on the diagnosis of neurodegenerative diseases: Sensing the past to the future |
|
|
| Münteha Nur Sonuç Karaboga, SezginturkMustafa Kemal Sezgintürk |
|
| Journal of Pharmaceutical and Biomedical Analysis. 2021; : 114479 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 43 |
Gauging the role and impact of drug interactions and repurposing in neurodegenerative disorders |
|
|
| Dharmendra Kumar Khatri,Amey Kadbhane,Monica Patel,Shweta Nene,Srividya Atmakuri,Saurabh Srivastava,Shashi Bala Singh |
|
| Current Research in Pharmacology and Drug Discovery. 2021; 2: 100022 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 44 |
Modulation of a-synuclein fibrillation by plant metabolites, daidzein, fisetin and scopoletin under physiological conditions |
|
|
| Ankita R. Rane,Harshad Paithankar,Ramakrishna V. Hosur,Sinjan Choudhary |
|
| International Journal of Biological Macromolecules. 2021; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 45 |
Prion-like C-Terminal Domain of TDP-43 and a-Synuclein Interact Synergistically to Generate Neurotoxic Hybrid Fibrils |
|
|
| Shailendra Dhakal,Courtney E. Wyant,Hannah E. George,Sarah E. Morgan,Vijayaraghavan Rangachari |
|
| Journal of Molecular Biology. 2021; 433(10): 166953 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 46 |
Ellagic Acid Modulates Uninduced as well as Mutation and Metal-Induced Aggregation of a-Synuclein: Implications for Parkinson’s Disease |
|
|
| Vinod Kumar Meena,Vijay Kumar,Shivani Karalia,Shivani Garima,Monica Sundd |
|
| ACS Chemical Neuroscience. 2021; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 47 |
Unraveling the NaCl Concentration Effect on the First Stages of a-Synuclein Aggregation |
|
|
| Rafael Ramis,Joaquín Ortega-Castro,Bartolomé Vilanova,Miquel Adrover,Juan Frau |
|
| Biomacromolecules. 2020; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 48 |
Anti-Parkinsonæs disease activity of phenolic acids from Eucommia ulmoides Oliver leaf extracts and their autophagy activation mechanism |
|
|
| Shanshan Zhang,Zhangping Yu,Jingyu Xia,Xuanming Zhang,Kechun Liu,Attila Sik,Meng Jin |
|
| Food & Function. 2020; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 49 |
Aggregation of biologically important peptides and proteins: inhibition or acceleration depending on protein and metal ion concentrations |
|
|
| Benjamin Gabriel Poulson,Kacper Szczepski,Joanna Izabela Lachowicz,Lukasz Jaremko,Abdul-Hamid Emwas,Mariusz Jaremko |
|
| RSC Advances. 2020; 10(1): 215 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 50 |
Identification of on- and off-pathway oligomers in amyloid fibril formation |
|
|
| Alexander J. Dear,Georg Meisl,Andela Šaric,Thomas C. T. Michaels,Magnus Kjaergaard,Sara Linse,Tuomas P. J. Knowles |
|
| Chemical Science. 2020; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 51 |
Unravelling the effect of N(e)-(carboxyethyl)lysine on the conformation, dynamics and aggregation propensity of a-synuclein |
|
|
| Laura Mariño,Rafael Ramis,Rodrigo Casasnovas,Joaquín Ortega-Castro,Bartolomé Vilanova,Juan Frau,Miquel Adrover |
|
| Chemical Science. 2020; 11(12): 3332 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 52 |
CSF a-synuclein correlates with CSF neurogranin in late-life depression |
|
|
| Davide Bruno,Chelsea Reichert Plaska,Daniel P. A. Clark,Henrik Zetterberg,Kaj Blennow,Marcel M. Verbeek,Nunzio Pomara |
|
| International Journal of Neuroscience. 2020; : 1 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 53 |
Demonstration of brain region-specific neuronal vulnerability in human iPSC-based model of familial Parkinson’s disease |
|
|
| Razvan-Marius Brazdis,Julian E Alecu,Daniel Marsch,Annika Dahms,Katrin Simmnacher,Sandra Lörentz,Anna Brendler,Yanni Schneider,Franz Marxreiter,Laurent Roybon,Beate Winner,Wei Xiang,Iryna Prots |
|
| Human Molecular Genetics. 2020; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 54 |
Gut-Brain Axis in Parkinsonæs disease Etiology: The Role of Lipopolysaccharide |
|
|
| Dipita Bhattacharyya,Anirban Bhunia |
|
| Chemistry and Physics of Lipids. 2020; : 105029 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 55 |
Viral-based rodent and nonhuman primate models of multiple system atrophy: Fidelity to the human disease |
|
|
| David J. Marmion,Angela A. Rutkowski,Diptaman Chatterjee,Benjamin M. Hiller,Milton H. Werner,Erwan Bezard,Deniz Kirik,Thomas McCown,Steven J. Gray,Jeffrey H. Kordower |
|
| Neurobiology of Disease. 2020; : 105184 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 56 |
Remodeling microglia to a protective phenotype in Parkinson’s disease? |
|
|
| Ifeoluwa Oluleke Awogbindin,Ismail Ogunbayode Ishola,Marie-Kim St-Pierre,Micaël Carrier,Julie C. Savage,Thérèse Di Paolo,Marie-Ève Tremblay |
|
| Neuroscience Letters. 2020; : 135164 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 57 |
Overexpression of a-Synuclein Reorganises Growth Factor Profile of Human Astrocytes |
|
|
| Büsra Sengül,Erdinç Dursun,Alexei Verkhratsky,Duygu Gezen-Ak |
|
| Molecular Neurobiology. 2020; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 58 |
Mitochondrial Protein Import Dysfunction in Pathogenesis of Neurodegenerative Diseases |
|
|
| Shweta Goyal,Rajnish Kumar Chaturvedi |
|
| Molecular Neurobiology. 2020; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 59 |
Lipopolysaccharide Animal Models of Parkinson’s Disease: Recent Progress and Relevance to Clinical Disease |
|
|
| Isaac Deng,Frances Corrigan,Guangxi Zhai,Xin-Fu Zhou,Larisa Bobrovskaya |
|
| Brain, Behavior, & Immunity - Health. 2020; : 100060 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 60 |
6-Hydroxydopamine: a far from simple neurotoxin |
|
|
| Damir Varešlija,Keith F. Tipton,Gavin P. Davey,Andrew G. McDonald |
|
| Journal of Neural Transmission. 2020; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 61 |
Using NMR spectroscopy to investigate the role played by copper in prion diseases |
|
|
| Rawiah A. Alsiary,Mawadda Alghrably,Abdelhamid Saoudi,Suliman Al-Ghamdi,Lukasz Jaremko,Mariusz Jaremko,Abdul-Hamid Emwas |
|
| Neurological Sciences. 2020; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 62 |
Genetics of synucleins in neurodegenerative diseases |
|
|
| José Brás,Elizabeth Gibbons,Rita Guerreiro |
|
| Acta Neuropathologica. 2020; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 63 |
The contribution of Parkin, PINK1 and DJ-1 genes to selective neuronal degeneration in Parkinsonæs disease |
|
|
| Marc van der Vlag,Robbert Havekes,Pim R. A. Heckman |
|
| European Journal of Neuroscience. 2020; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 64 |
The Antiaggregative and Antiamyloidogenic Properties of Nanoparticles: A Promising Tool for the Treatment and Diagnostics of Neurodegenerative Diseases |
|
|
| Monika Pichla,Grzegorz Bartosz,Izabela Sadowska-Bartosz,Marco Malaguti |
|
| Oxidative Medicine and Cellular Longevity. 2020; 2020: 1 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 65 |
Alleviating toxic a-Synuclein accumulation by membrane depolarization: evidence from an in vitro model of Parkinson’s disease |
|
|
| Alysia Ross,Viktoria Xing,Ting Ting Wang,Samantha C. Bureau,Giovana A. Link,Teresa Fortin,Hui Zhang,Shawn Hayley,Hongyu Sun |
|
| Molecular Brain. 2020; 13(1) |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 66 |
Eye lens crystallin proteins inhibit the autocatalytic amyloid amplification nature of mature a-synuclein fibrils |
|
|
| Ricardo Gaspar,Tommy Garting,Anna Stradner,Peter Schuck |
|
| PLOS ONE. 2020; 15(6): e0235198 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 67 |
Identifying the mechanisms of a-synuclein-mediated cytotoxicity in Parkinson’s disease: new insights from a bioinformatics-based approach |
|
|
| Sankha S Chakrabarti,Venkatadri S Sunder,Upinder Kaur,Sapna Bala,Priyanka Sharma,Manjari Kiran,Ravindra K Rawal,Sasanka Chakrabarti |
|
| Future Neurology. 2020; : FNL49 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 68 |
Using CRISPR-X for Optimization of Antibodies Towards A30P a-synuclein Oligomers in Immunotherapy of Parkinson’s Disease |
|
|
| Isabell C. Pitigoi, Courtney E. Ostromecki |
|
| Undergraduate Research in Natural and Clinical Science and Technology (URNCST) Journal. 2020; 4(7): 1 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 69 |
Linking Alpha-Synuclein to the Actin Cytoskeleton: Consequences to Neuronal Function |
|
|
| Marina I. Oliveira da Silva,Márcia A. Liz |
|
| Frontiers in Cell and Developmental Biology. 2020; 8 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 70 |
Intracellular Alpha-Synuclein and Immune Cell Function |
|
|
| Veselin Grozdanov,Karin M. Danzer |
|
| Frontiers in Cell and Developmental Biology. 2020; 8 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 71 |
From Seeds to Fibrils and Back: Fragmentation as an Overlooked Step in the Propagation of Prions and Prion-Like Proteins |
|
|
| Cristóbal Marrero-Winkens,Charu Sankaran,Hermann M. Schätzl |
|
| Biomolecules. 2020; 10(9): 1305 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 72 |
Alpha-Synuclein Physiology and Pathology: A Perspective on Cellular Structures and Organelles |
|
|
| Luis D. Bernal-Conde,Rodrigo Ramos-Acevedo,Mario A. Reyes-Hernández,Andrea J. Balbuena-Olvera,Ishbelt D. Morales-Moreno,Rubén Argüero-Sánchez,Birgitt Schüle,Magdalena Guerra-Crespo |
|
| Frontiers in Neuroscience. 2020; 13 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 73 |
Cynomolgus Monkeys With Spontaneous Type-2-Diabetes-Mellitus-Like Pathology Develop Alpha-Synuclein Alterations Reminiscent of Prodromal Parkinson’s Disease and Related Diseases |
|
|
| Yan Sun,Chuang Guo,Lin Yuan,Wen Li,Zhan-You Wang,Feng Yue,Jia-Yi Li |
|
| Frontiers in Neuroscience. 2020; 14 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 74 |
Looking Beyond the Core: The Role of Flanking Regions in the Aggregation of Amyloidogenic Peptides and Proteins |
|
|
| Sabine M. Ulamec,David J. Brockwell,Sheena E. Radford |
|
| Frontiers in Neuroscience. 2020; 14 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 75 |
Endosomal-Lysosomal Processing of Neurodegeneration-Associated Proteins in Astrocytes |
|
|
| Ching-On Wong |
|
| International Journal of Molecular Sciences. 2020; 21(14): 5149 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 76 |
Antibody Fragments as Tools for Elucidating Structure-Toxicity Relationships and for Diagnostic/Therapeutic Targeting of Neurotoxic Amyloid Oligomers |
|
|
| André L. B. Bitencourt,Raquel M. Campos,Erika N. Cline,William L. Klein,Adriano Sebollela |
|
| International Journal of Molecular Sciences. 2020; 21(23): 8920 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 77 |
pH-Dependent Aggregation in Intrinsically Disordered Proteins Is Determined by Charge and Lipophilicity |
|
|
| Jaime Santos,Valentín Iglesias,Juan Santos-Suárez,Marco Mangiagalli,Stefania Brocca,Irantzu Pallarès,Salvador Ventura |
|
| Cells. 2020; 9(1): 145 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 78 |
Novel Immunotherapeutic Approaches to Target Alpha-Synuclein and Related Neuroinflammation in Parkinson’s Disease |
|
|
| Maria Zella,Judith Metzdorf,Friederike Ostendorf,Fabian Maass,Siegfried Muhlack,Ralf Gold,Aiden Haghikia,Lars Tönges |
|
| Cells. 2019; 8(2): 105 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 79 |
Prion and Prion-Like Protein Strains: Deciphering the Molecular Basis of Heterogeneity in Neurodegeneration |
|
|
| Carlo Scialò,Elena De Cecco,Paolo Manganotti,Giuseppe Legname |
|
| Viruses. 2019; 11(3): 261 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 80 |
Mechanical and thermodynamic properties of Aß42, Aß40, and a-synuclein fibrils: a coarse-grained method to complement experimental studies |
|
|
| Adolfo B Poma,Horacio V Guzman,Mai Suan Li,Panagiotis E Theodorakis |
|
| Beilstein Journal of Nanotechnology. 2019; 10: 500 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 81 |
Implications of alpha-synuclein nitration at tyrosine 39 in methamphetamine-induced neurotoxicity in vitro and in vivo |
|
|
| Hong-Hua Qiao,Lin-Nan Zhu,Yue Wang,Jia-Liang Hui,Wei-Bing Xie,Chao Liu,Ling Chen,Ping-Ming Qiu |
|
| Neural Regeneration Research. 2019; 14(2): 319 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 82 |
Lipids at the Crossroad of a-Synuclein Function and Dysfunction: Biological and Pathological Implications |
|
|
| Natalia P. Alza,Pablo A. Iglesias González,Melisa A. Conde,Romina M. Uranga,Gabriela A. Salvador |
|
| Frontiers in Cellular Neuroscience. 2019; 13 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 83 |
Naphthoquinone Tryptophan Hybrids: A Promising Small Molecule Scaffold for Mitigating Aggregation of Amyloidogenic Proteins and Peptides |
|
|
| Guru KrishnaKumar Viswanathan,Ashim Paul,Ehud Gazit,Daniel Segal |
|
| Frontiers in Cell and Developmental Biology. 2019; 7 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 84 |
Physiological, molecular and genetic aspects of alpha-synuclein and its correlation with high alcohol consumption |
|
|
| Tania Yadira Martínez-Rodríguez,Mauricio Rey-Buitrago |
|
| Revista de la Facultad de Medicina. 2019; 67(3): 315 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 85 |
Early stages of Parkinson’s disease: aspects of the diagnosis and therapy |
|
|
| A. A. Pilipovich |
|
| Medical Council. 2019; (18): 61 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 86 |
a-synuclein-lipoprotein interactions and elevated ApoE level in cerebrospinal fluid from Parkinsonæs disease patients |
|
|
| Wojciech Paslawski,Justyna Zareba-Paslawska,Xiaoqun Zhang,Katharina Hölzl,Henrik Wadensten,Mohammadreza Shariatgorji,Shorena Janelidze,Oskar Hansson,Lars Forsgren,Per E. Andrén,Per Svenningsson |
|
| Proceedings of the National Academy of Sciences. 2019; : 201821409 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 87 |
Selective vulnerability in a-synucleinopathies |
|
|
| Javier Alegre-Abarrategui,Katherine R. Brimblecombe,Rosalind F. Roberts,Elisavet Velentza-Almpani,Bension S. Tilley,Nora Bengoa-Vergniory,Christos Proukakis |
|
| Acta Neuropathologica. 2019; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 88 |
Plasma a
-synuclein levels are increased in patients with obstructive sleep apnea syndrome |
|
|
| Hao-Lun Sun,Bin-Lu Sun,Dong-Wan Chen,Yang Chen,Wei-Wei Li,Man-Yu Xu,Ying-Ying Shen,Zhi-Qiang Xu,Yan-Jiang Wang,Xian-Le Bu |
|
| Annals of Clinical and Translational Neurology. 2019; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 89 |
In-vitro and in-silico investigation of protective mechanisms of crocin against E46K a-synuclein amyloid formation |
|
|
| Marzieh Ghasemi Tigan,Arezou Ghahghaei,Milad Lagzian |
|
| Molecular Biology Reports. 2019; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 90 |
Reprint of “Ganglioside lipids accelerate a-synuclein amyloid formation” |
|
|
| Ricardo Gaspar,Jon Pallbo,Ulrich Weininger,Sara Linse,Emma Sparr |
|
| Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 2019; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 91 |
Prion Efficiently Replicates in a-Synuclein Knockout Mice |
|
|
| Edoardo Bistaffa,Martina Rossi,Chiara Maria Giulia De Luca,Federico Cazzaniga,Olga Carletta,Ilaria Campagnani,Fabrizio Tagliavini,Giuseppe Legname,Giorgio Giaccone,Fabio Moda |
|
| Molecular Neurobiology. 2019; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 92 |
The Role of Aptamer Loaded Exosome Complexes in the Neurodegenerative Diseases |
|
|
| Simranjeet Singh Sekhon,Gna Ahn,Ga-Young Park,Dae-Young Park,Sang-Hee Lee,Ji-Young Ahn,Yang-Hoon Kim |
|
| Toxicology and Environmental Health Sciences. 2019; 11(2): 85 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 93 |
Recent advances of induced pluripotent stem cells application in neurodegenerative diseases |
|
|
| Nashwa Amin,Xiaoning Tan,Qiannan Ren,Ning Zhu,Benson O.A. Botchway,Zhiying Hu,Marong Fang |
|
| Progress in Neuro-Psychopharmacology and Biological Psychiatry. 2019; 95: 109674 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 94 |
Alpha synuclein in hematopoiesis and immunity |
|
|
| Yu Pei,Robert W. Maitta |
|
| Heliyon. 2019; 5(10): e02590 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 95 |
Deciphering the anti-Parkinson’s activity of sulphated polysaccharides from Chlamydomonas reinhardtii on the a-Synuclein mutants A30P, A53T, E46K, E57K and E35K |
|
|
| Gitanjali P Panigrahi,Ankita R Rane,Sirisha L Vavilala,Sinjan Choudhary |
|
| The Journal of Biochemistry. 2019; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 96 |
Upcoming diagnostic biomarkers with promising prospects in neurological disorders |
|
|
| Wasim Ahmad,Abuzer Ali,Amena Ali,Sana Khan,Saba Khan,Ibraheem Husain |
|
| Clinical and Experimental Pharmacology and Physiology. 2019; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 97 |
A Coarse-Grained Molecular Dynamics Approach to the Study of the Intrinsically Disordered Protein a-Synuclein |
|
|
| Rafael Ramis,Joaquín Ortega-Castro,Rodrigo Casasnovas,Laura Mariño,Bartolomé Vilanova,Miquel Adrover,Juan Frau |
|
| Journal of Chemical Information and Modeling. 2019; 59(4): 1458 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 98 |
Mass Spectrometric Analysis of Lewy Body-Enriched a-Synuclein in Parkinson’s Disease |
|
|
| Payel Bhattacharjee,Annika Öhrfelt,Tammaryn Lashley,Kaj Blennow,Ann Brinkmalm,Henrik Zetterberg |
|
| Journal of Proteome Research. 2019; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 99 |
Recent progress of drug nanoformulations targeting to brain |
|
|
| Abdur Rauf Khan,Xiaoye Yang,Manfei Fu,Guangxi Zhai |
|
| Journal of Controlled Release. 2018; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 100 |
The Cellular Environment Affects Monomeric a-Synuclein Structure |
|
|
| Amberley D. Stephens,Maria Zacharopoulou,Gabriele S. Kaminski Schierle |
|
| Trends in Biochemical Sciences. 2018; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 101 |
Alpha-synuclein mitochondrial interaction leads to irreversible translocation and complex I impairment |
|
|
| Jimena H. Martínez,Federico Fuentes,Virginia Vanasco,Silvia Alvarez,Agustina Alaimo,Adriana Cassina,Federico Coluccio Leskow,Francisco Velazquez |
|
| Archives of Biochemistry and Biophysics. 2018; 651: 1 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 102 |
Post-translational modifications of Parkinsonæs disease-related proteins: Phosphorylation, SUMOylation and ubiquitination |
|
|
| Stella C. Junqueira,Eduarda G.Z. Centeno,Kevin A. Wilkinson,Helena Cimarosti |
|
| Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 2018; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 103 |
The role of posttranslational modifications of a-synuclein and LRRK2 in Parkinsonæs disease: Potential contributions of environmental factors |
|
|
| Edward Pajarillo,Asha Rizor,Jayden Lee,Michael Aschner,Eunsook Lee |
|
| Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 2018; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 104 |
Salt-bridge dynamics in intrinsically disordered proteins: A trade-off between electrostatic interactions and structural flexibility |
|
|
| Sankar Basu,Parbati Biswas |
|
| Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 2018; 1866(5-6): 624 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 105 |
Ganglioside lipids accelerate a-synuclein amyloid formation |
|
|
| Ricardo Gaspar,Jon Pallbo,Ulrich Weininger,Sara Linse,Emma Sparr |
|
| Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 2018; 1866(10): 1062 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 106 |
Alpha-Synuclein Toxicity on Protein Quality Control, Mitochondria and Endoplasmic Reticulum |
|
|
| Thaiany Quevedo Melo,Sjef J. C. V. M. Copray,Merari F. R. Ferrari |
|
| Neurochemical Research. 2018; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 107 |
Using Patient-Derived Induced Pluripotent Stem Cells to Identify Parkinson’s Disease-Relevant Phenotypes |
|
|
| S. L. Sison,S. C. Vermilyea,M. E. Emborg,A. D. Ebert |
|
| Current Neurology and Neuroscience Reports. 2018; 18(12) |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 108 |
Cellular Proteostasis in Neurodegeneration |
|
|
| Alberim Kurtishi,Benjamin Rosen,Ketan S. Patil,Guido W. Alves,Simon G. Møller |
|
| Molecular Neurobiology. 2018; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 109 |
Formation of Heterotypic Amyloids: a-Synuclein in Co-Aggregation |
|
|
| Karishma Bhasne,Samrat Mukhopadhyay |
|
| PROTEOMICS. 2018; : 1800059 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 110 |
Crucial role of protein oligomerization in the pathogenesis of Alzheimeræs and Parkinsonæs diseases |
|
|
| Minee L. Choi,Sonia Gandhi |
|
| The FEBS Journal. 2018; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 111 |
Effect of rs3910105 in the Synuclein Gene on Dopamine Transporter Availability in Healthy Subjects |
|
|
| Youngduk Seo,Kyoungjune Pak,Hyun-Yeol Nam,Ju Won Seok,Myung Jun Lee,Eun-Joo Kim,Jae Meen Lee,Seong Jang Kim,In Joo Kim |
|
| Yonsei Medical Journal. 2018; 59(6): 787 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 112 |
Clearing Extracellular Alpha-Synuclein from Cerebrospinal Fluid: A New Therapeutic Strategy in Parkinson’s Disease |
|
|
| Manuel Menéndez-González,Huber Padilla-Zambrano,Cristina Tomás-Zapico,Benjamin García |
|
| Brain Sciences. 2018; 8(4): 52 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 113 |
Parkinson’s Disease: Biomarkers, Treatment, and Risk Factors |
|
|
| Fatemeh N. Emamzadeh,Andrei Surguchov |
|
| Frontiers in Neuroscience. 2018; 12 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 114 |
Comparing the Folds of Prions and Other Pathogenic Amyloids |
|
|
| José Flores-Fernández,Vineet Rathod,Holger Wille |
|
| Pathogens. 2018; 7(2): 50 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 115 |
Insights into the Molecular Mechanisms of Alzheimer’s and Parkinson’s Diseases with Molecular Simulations: Understanding the Roles of Artificial and Pathological Missense Mutations in Intrinsically Disordered Proteins Related to Pathology |
|
|
| Orkid Coskuner-Weber,Vladimir Uversky |
|
| International Journal of Molecular Sciences. 2018; 19(2): 336 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 116 |
a-Synuclein aggregation modulation: an emerging approach for the treatment of Parkinsonæs disease |
|
|
| Sushil K Singh,Aloke Dutta,Gyan Modi |
|
| Future Medicinal Chemistry. 2017; 9(10): 1039 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 117 |
Synucleins and Gene Expression: Ramblers in a Crowd or Cops Regulating Traffic? |
|
|
| Alexei A. Surguchev,Andrei Surguchov |
|
| Frontiers in Molecular Neuroscience. 2017; 10 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 118 |
Finding a new purpose for old drugs |
|
|
| Evan Y. Snyder |
|
| Science. 2017; 357(6354): 869 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 119 |
Up-regulation of autophagy-related gene 5 (ATG5) protects dopaminergic neurons in a zebrafish model of Parkinsonæs disease |
|
|
| Zhan-ying Hu,Bo Chen,Jing-pu Zhang,Yuan-yuan Ma |
|
| Journal of Biological Chemistry. 2017; 292(44): 18062 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 120 |
Bone loss in C57BL/6J-OlaHsd mice, a substrain of C57BL/6J carrying mutated alpha-synuclein and multimerin-1 genes |
|
|
| Tamar Liron,Bitya Raphael,Sahar Hiram-Bab,Itai A. Bab,Yankel Gabet |
|
| Journal of Cellular Physiology. 2017; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 121 |
iPS cells in the study of PD molecular pathogenesis |
|
|
| Melanie M. Cobb,Abinaya Ravisankar,Gaia Skibinski,Steven Finkbeiner |
|
| Cell and Tissue Research. 2017; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 122 |
Ginkgolide K promotes the clearance of A53T mutation alpha-synuclein in SH-SY5Y cells |
|
|
| Wenbo Yu,Sheng Chen,Liang Cao,Jie Tang,Wei Xiao,Baoguo Xiao |
|
| Cell Biology and Toxicology. 2017; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 123 |
Role of Apolipoproteins and a-Synuclein in Parkinson’s Disease |
|
|
| Fatemeh Nouri Emamzadeh |
|
| Journal of Molecular Neuroscience. 2017; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 124 |
DT-diaphorase Protects Against Autophagy Induced by Aminochrome-Dependent Alpha-Synuclein Oligomers |
|
|
| Patricia S. Muñoz,Juan Segura-Aguilar |
|
| Neurotoxicity Research. 2017; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 125 |
Small molecule probes of protein aggregation |
|
|
| Lydia M Young,Alison E Ashcroft,Sheena E Radford |
|
| Current Opinion in Chemical Biology. 2017; 39: 90 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 126 |
Correlation of Plasma EGF with Striatal Dopamine Transporter Availability in Healthy Subjects |
|
|
| Kyoungjune Pak,Seunghyeon Shin,So Jung Kim,Keunyoung Kim,Bum Soo Kim,Seong Jang Kim,In Joo Kim |
|
| Scientific Reports. 2017; 7(1) |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 127 |
Familial Mutations May Switch Conformational Preferences in a-Synuclein Fibrils |
|
|
| Liang Xu,Buyong Ma,Ruth Nussinov,Damien Thompson |
|
| ACS Chemical Neuroscience. 2017; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
