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Year : 2021  |  Volume : 26  |  Issue : 1  |  Page : 40

Mortality and characteristics of older people dying with COVID-19 in Lombardy nursing homes, Italy: An observational cohort study

1 IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy
2 IRCCS Fondazione Don Carlo Gnocchi, Florence; The BioRobotics Institute, Scuola Superiore Sant'Anna, Pisa, Italy
3 IRCCS Fondazione Don Carlo Gnocchi, Florence, Italy
4 IRCCS Fondazione Don Carlo Gnocchi, Milan; The BioRobotics Institute, Scuola Superiore Sant'Anna, Pisa, Italy

Correspondence Address:
Dr. Chiara Arienti
IRCCS Fondazione Don Carlo Gnocchi, Via Alfonso Capecelatro, Milan
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jrms.JRMS_1012_20

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Background: The aim of the study was to describe the epidemiological characteristics of Nursing Homes (NHs) residents infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and to compute the related case-fatality rate. Materials and Methods: The outcomes were mortality and case-fatality rate with related epidemiological characteristics (age, sex, comorbidity, and frailty). Results: During the COVID-19 outbreak lasted from March 1 to May 7, 2020, 330 residents died in Fondazione Don Gnocchi NHs bringing the mortality rate to 27% with a dramatic increase compared to the same period of 2019, when it was 7.5%. Naso/oropharyngeal swabs resulted positive for COVID-19 in 315 (71%) of the 441of the symptomatic/exposed residents tested. The COVID-19 population was 75% female, with a 17% overall fatality rate and sex-specific fatality rates of 19% and 13% for females and males, respectively. Fifty-six percent of deaths presented SARS-CoV-2-associated pneumonia, 15% cardiovascular, and 29% miscellaneous pathologies. Conclusion: Patients' complexity and frailty might influence SARS-CoV-2 infection case-fatality rate estimates. A COVID-19 register is needed to study COVID-19 frail patients' epidemiology and characteristics.

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